儿茶酚胺血检

定义

This test measures the levels of catecholamines in the blood. Catecholamines are hormones made by the adrenal glands. The three catecholamines are epinephrine (adrenaline), 去甲肾上腺素, and dopamine.

Catecholamines are more often measured with a 尿检 比验血更重要.

选择的名字

Norepinephrine - blood; Epinephrine - blood; Adrenaline - blood; Dopamine - blood

How the Test is Performed

A 血液样本 是必要的.

How to Prepare for the Test

You will likely be told not to eat anything (fast) for 10 hours before the test. You may be allowed to drink water during this time.

The accuracy of the test can be affected by certain foods and medicines. Foods that can increase catecholamine levels include:

• 咖啡
• 茶
• 香蕉
• 巧克力
• 可可
• 柑橘类水果
• 香草

You should not eat these foods for several days before the test. This is especially true if both blood and urine catecholamines are to be measured.

You should also avoid stressful situations and vigorous exercise. Both can affect the accuracy of the test results.

Medicines and substances that can increase catecholamine measurements include:

• 对乙酰氨基酚
• 沙丁胺醇
• 氨茶碱
• 安非他明
• 丁螺环酮
• 咖啡因
• 钙通道阻滞剂
• 可卡因
• 环苯扎林
• 左旋多巴
• 甲基多巴
• 尼古丁
• 烟酸 (大剂量)
• 酚苄明
• 吩噻嗪类
• 伪麻黄碱
• 利血平
• Tricyclic antidepressants

Medicines that can decrease catecholamine measurements include:

• 可乐定
• 胍乙啶
• Monoamine oxidase (MAO) inhibitors

If you take any of the above medicines, check with your health care provider before the blood test about whether you should stop taking your medicine.

考试的感觉如何

When the needle is inserted to draw blood, some people feel slight pain. Others feel a prick or stinging. Afterward, there may be some throbbing or a slight bruise. 这很快就会消失.

Why the Test is Performed

Catecholamines are released into the blood when a person is under physical or emotional stress. The main catecholamines are dopamine, 去甲肾上腺素, and epinephrine (which used to be called adrenalin).

This test is used to diagnose or rule out certain rare tumors, such as 嗜铬细胞瘤 or 神经母细胞瘤. It may also be done in people with those conditions to determine if treatment is working.

正常的结果

The normal range for epinephrine is 0 to 140 pg/mL (764.3 pmol / L).

The normal range for 去甲肾上腺素 is 70 to 1700 pg/mL (413.8 to 10048.7 pmol / L).

The normal range for dopamine is 0 to 30 pg/mL (195.8 pmol / L).

Note: Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your provider about the meaning of your specific test results.

What Abnormal Results Mean

Higher-than-normal levels of blood catecholamines may suggest:

• 急性焦虑
• Ganglioblastoma (非常罕见的肿瘤)
• 星形胶质细胞瘤 (非常罕见的肿瘤)
• Neuroblastoma (rare tumor)
• Pheochromocytoma (rare tumor)
• 严重的压力

Additional conditions under which the test may be performed include 多系统萎缩.

风险

There is little risk in having your blood taken. Veins and arteries vary in size from one person to another and from one side of the body to the other. Taking blood from some people may be more difficult than from others.

Other risks associated with having blood drawn are slight, but may include:

• 大出血
• Fainting or feeling lightheaded
• Multiple punctures to locate veins
• Hematoma (blood accumulating under the skin)
• Infection (a slight risk any time the skin is broken)

参考文献

Guber HA, Oprea M, Russell YX. Evaluation of endocrine function. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24日艾德. Philadelphia, PA: Elsevier; 2022:chap 25.

年轻的WF. Adrenal medulla, catecholamines, and 嗜铬细胞瘤. In: Goldman L, Schafer AI, eds. Goldman-Cecil医学. 26日艾德. Philadelphia, PA: Elsevier; 2020:chap 215.